​Charles P. Venditti, MD

Dr. Venditti is an Investigator in the National Human Genome Research Institute and the Director of the Organic Acid Research Unit at the National Institutes of Health in Bethesda, MD. He received his BS from MIT in 1988 and was an MD, PhD scholarship recipient at Penn State University between 1989-1996. After graduation, he completed a pediatrics residency at Massachusetts General Hospital/Harvard Medical School (1996-1999) and a human genetics fellowship at the Children’s Hospital of Philadelphia/University of Pennsylvania School of Medicine (1999-2003). He is board-certified in pediatrics, clinical and biochemical genetics and is an Attending Physician at the Mark O. Hatfield Clinical Center at the NIH, where he has initiated a translational research program to study the natural history and clinical phenotype(s) of the hereditary methylmalonic acidemias (MMA).  The laboratory investigations use genetic, genomic and biochemical approaches to examine organic acid metabolism in experimental animals, including yeast, roundworms and mice. The goals of the research are to create, manipulate and study model-organism systems that can then be used to evaluate therapies for MMA, to examine and characterize genetic determinants of propionate, MMA and vitamin B12 metabolism and to identify new genes and metabolic pathways perturbed in MMA. He is a member of the Society of Inherited Metabolic Disease, has authored and co-authored more than 50 research articles, clinical reports, textbook chapters and serves on the advisory board of the Organic Acidemia Association.